OpenTox - An open source predictive toxicology Framework (OPENTOX)

Description: Das Projekt "OpenTox - An open source predictive toxicology Framework (OPENTOX)" wird vom Umweltbundesamt gefördert und von Fraunhofer-Institut für Toxikologie und Experimentelle Medizin (ITEM) durchgeführt. The goal of the OpenTox project is to develop a predictive toxicology framework with a unified access to toxicological data, (Q)SAR models and supporting information. It will provide tools for the integration of data from various sources (public and confidential), for the generation and validation of (Q)SAR models, libraries for the development and integration of new (Q)SAR algorithms, and validation routines. OpenTox will attract toxicological experts without (Q)SAR expertise as well as model and algorithm developers. It will move beyond existing attempts to solve individual research issues, by providing a flexible and user friendly framework that integrates existing solutions and new developments. OpenTox will be relevant for REACH as it gives risk assessors simple access to experimental data, (Q)SAR models and toxicological information that adheres to European and international regulatory requirements. OpenTox will be published as an open source project to allow a critical evaluation of its algorithms, to promote dissemination, and to attract external developers. Facilities for the inclusion of confidential in-house data and for accessing commercial prediction systems will be included. OpenTox will contain high-quality data and (Q)SAR models for chronic, genotoxic and carcinogenic effects. Prime Contractor: Douglas Connect; Zeiningen; Schweiz.

Types:

SupportProgram

Origin: /Bund/UBA/UFORDAT

Tags: Kanzerogenität ? Schweiz ? Genotoxizität ? Struktur-Wirkung-Beziehung ? Berechnungsverfahren ? Daten ? Toxikologie ? REACH ? Datenbank ? Datenerhebung ? Gutachten ? Risiko ? (Q)SAR ? Medical biotechnology ? in silico ? open source ? predictive toxicology ? reduction ? reduction of animal experiments, ?

Region: Lower Saxony

Bounding box: 9.16667° .. 9.16667° x 52.83333° .. 52.83333°

License: cc-by-nc-nd/4.0

Language: Deutsch

Organisations

• Albert-Ludwigs-Universität Freiburg (Mitwirkende)
• Douglas Connect (Mitwirkende)
• Fraunhofer-Institut für Toxikologie und Experimentelle Medizin (Betreiber*in)
• Helma Christoph (Mitwirkende)
• Ideaconsult LTD (Mitwirkende)
• Institute of Biomedical Chemistry of Russian Academy of Medical Sciences (Mitwirkende)
• Istituto Superiore di Sanita (Mitwirkende)
• Kommission der Europäischen Gemeinschaften Brüssel (Bereitsteller*in)
• National Technical University of Athens (Mitwirkende)
• SEASCAPE LEARNING CO PRIVATE LTD (Mitwirkende)
• Technische Universität München (Mitwirkende)
• Umweltbundesamt (Bereitsteller*in)

Time ranges: 2008-09-01 - 2011-08-31

Alternatives

• Language: Englisch/English https://ufordat.uba.de/

Status

Aktiv

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