Description: Das Projekt "Fate of viruses in surface water: the effect of iron-based particles on virus inactivation" wird vom Umweltbundesamt gefördert und von Ecole Polytechnique Federale de Lausanne (EPF), Institut d'Amenagement des Terres et des Eaux (IATE) durchgeführt. Despite the remarkable progress accomplished in water and wastewater treatment over the past decades, viral pathogens in drinking and recreational water continue to pose a threat to public health in both industrialized and developing nations. Some of the most effective treatment methods to enhance microbial water quality (e.g., waste stabilization ponds) rely on naturally occurring disinfection processes typically encountered in surface water. Even though such treatment methods are extensively used, little is known about the factors that govern virus inactivation. In particular, the interaction of viruses with suspended particles may affect inactivation, but the interconnection is complex and not well understood; particles have been shown to both increase and decrease virus inactivation compared to free viruses. An in-depth understanding of the effects of particle association on virus survival is crucial to assess and control the fate of viruses in both natural and engineered surface water systems. The overall goal of this project is to determine how adsorption onto particles influences naturally occurring virus inactivation processes in the dark and under sunlight. The involvement of sunlight is a key component of this project because it is an important contributor to virus inactivation in surface water. A range of iron-based particles with varying surface properties will serve as the model for naturally occurring particles, and a selection of bacteriophages of different sizes and genome types will be used as surrogates for human viruses. Specific objectives are to I) quantify virus adsorption and particle-mediated inactivation in the dark, and establish whether an interrelation between the two processes exists; II) determine if photooxidants produced by the particles upon illumination by sunlight enhance particle-mediated inactivation, and characterize the dominant inactivation mechanisms; and III) assess if infective viruses can be released from particles upon changes in the solution conditions. A combination of photochemical techniques, molecular biological methods, and state-of-the-art surface analyses will be used to address the project objectives. Our findings will significantly augment our current knowledge of the fate of viruses in surface waters. They will improve the assessment of the public health risk posed by viral contamination of water systems, and they will offer insight into better ways to control the discharge of pathogenic viruses into the environment.
SupportProgram
Origin: /Bund/UBA/UFORDAT
Tags: Abwasserteich ? Genom ? Eisen ? Textilchemikalien ? Abfallbehandlung ? Schwebstoff ? Brunnen ? Abfluss ? Abwasserbehandlung ? Adsorption ? Bakteriophagen ? Partikelemission ? Wirkung ? Wasserverschmutzung ? Gesundheitliche Bewertung ? Beleuchtung ? Bewässerung ? Bewertung ? Desinfektion ? Getränk ? Gewässerqualität ? Mensch ? Oberflächengewässer ? Staat ? Technik ? Virus ? Allgemeine Gesundheit ? Wasserqualität ? Wasser ? Wirkung ? Aufbereitungstechnik ? Krankheitserreger ? Partikel ? Risiko ? Solarstrahlung ? Umwelt ? Abfall ? Abwasser ? Verunreinigung ? KONTROLLE ? LOESUNG ? OBERFLAECHE ? PROJEKT ? FORTSCHRITT ? SPEZIFISCH ? UEBERLEBEN ? UNTER ? VERARBEITEN ? VERBAND ? VERBLEIB ? FREI ? VERGLEICHEN ? GEMISCHT ? VERHAELTNIS ? Vermehrung ? Virusinaktivierung ? WICHTIG ? BESTANDTEIL ? BESTEHEND ? BEWERTEN ? ABNAHME ? Geisteswissenschaften ? INGENIEURWESEN ? Auslese ? BIOLOGISCH ? Bemessung ? MECHANISMEN ? Buchgrundstück ? METHODE ? MISCHUNG ? LAENDER ?
License: cc-by-nc-nd/4.0
Language: Englisch/English
Time ranges: 2007-12-01 - 2010-11-30
Accessed 1 times.