Development of a platform and toolkit for understanding interactions between nanoparticles and the living world (NANOINTERACT)

Description: Das Projekt "Development of a platform and toolkit for understanding interactions between nanoparticles and the living world (NANOINTERACT)" wird/wurde gefördert durch: Kommission der Europäischen Gemeinschaften Brüssel. Es wird/wurde ausgeführt durch: University College Dublin, National University of Ireland, School of Chemistry, Conway Institute of Biomolecular and Biomedical Research.Objective: We combine state-of-the-art techniques, methodologies, skills and instrumentation from several scientific arenas to create discipline-independent platforms to address key questions in nanotoxicology. Thus, we identify the routes via which nanoparticles enter and accumulate in living organisms, and connect this to representative cell-nanoparticle systems. Then using the most advanced methods of chemical, physical, biological and toxicological sciences we connect nanoparticle properties (in physiological conditions) to the mechanisms via which they interact with, and disrupt, cellular processes. We establish means and protocols via which every step of the program will be controlled, eliminating the factors that currently cause irreproducibilities. We emphasize novel unbiased assessments of intra- and inter-cellular processes after exposure to nanoparticles, enabling us to explore known, and unknown, processes. Key companies, large and small from several end-user groups, that are currently facing the challenge of applying nanotechnology in their products are built into the program in a substantial manner, and other key stake-holders are also incorporated into the overall consortium via the Advisory Board. This will ensure maximum uptake of the knowledge generated by NanoInteract, and enable development of Standards for nanoparticle risk assessment.

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Origins: /Bund/UBA/UFORDAT

Tags: Physiologische Wirkung ? Schadstoffwirkung ? Irland ? Chemische Analyse ? Schadstoffexposition ? Eintragspfad ? Bioakkumulation ? Interdisziplinarität ? Risikoanalyse ? Werkstoffkunde ? Wirkungsanalyse ? Zelle ? Schule ? Biologische Untersuchung ? Nanopartikel ? Aufbereitungstechnik ? Organismen ? Schadstoffakkumulation ? Schadstoffverhalten ? Physikalischer Vorgang ? Nanotechnologie ? Risikobewertung ? FP6-NMP ? Industrial Manufacture ? Interaktionsanalyse ? Nanotoxikologie ? Nanotoxizität ? Wechselwirkung ? Zellphysiologie ?

License: cc-by-nc-nd/4.0

Language: Englisch/English

Organisations

• DSM Innovation Center B.V., Biomedical (Mitwirkende)
• Glantreo Ltd. (Mitwirkende)
• Kommission der Europäischen Gemeinschaften Brüssel (Bereitsteller*in)
• L'Oreal (Mitwirkende)
• Medtronic Bakken Research Center B.V., Biomaterials Technology (Mitwirkende)
• The Weizmann Institute of Science, Materials and Interfaces Department, Faculty of Chemistry, Weizmann Institute (Mitwirkende)
• Umicore SA,NV Corporate EHS (Mitwirkende)
• Umweltbundesamt (Bereitsteller*in)
• University College Dublin, National University of Ireland, School of Chemistry, Conway Institute of Biomolecular and Biomedical Research (Betreiber*in)
• University Oxford, Physical and Theoretical Chemistry Laboratory (Mitwirkende)
• Universität München, Institute for Experimental Physics Biophysics and Soft Condensed Matter Physics (Mitwirkende)
• William Marsh Rice University, Richard E. Smalley Institute for Nanoscale Science and Technology (Mitwirkende)

Time ranges: 2007-01-01 - 2009-12-31

Resources

• Webseite zum Förderprojekt

  http://www.nanointeract.net/ (Webseite)

Status

Aktiv

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