Description: Das Projekt "Physical and chemical processes that lead to virus inactivation at solid-water interfaces - a combined computational and experimental approach" wird/wurde gefördert durch: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung. Es wird/wurde ausgeführt durch: Ecole Polytechnique Federale de Lausanne (EPF), Institut d'Amenagement des Terres et des Eaux (IATE).Virus inactivation processes at water-solid interfaces are key factors determining the persistence of viruses in various aqueous environments. These include environmental systems such as surface and groundwater, various food products, and blood and other bodily fluids. Once released into a body of water, viruses rapidly associate with water-solid interfaces. Interactions with solid surfaces influence virus disinfection, and thus determine the spread and persistence of infective viruses. Despite the importance of interfacial disinfection processes, their underlying causes remain poorly understood. In this sinergia project, we will identify the most important processes contributing to virus inactivation at interfaces, and we will develop a comprehensive model of the virus characteristics and surface properties that influence inactivation behavior. Our investigations will focus on model systems representative of one of the great challenges to public health, namely water resources contaminated by viral pathogens. To obtain a system characterization at the molecular level, we will use a combined computational and experimental approach. This project is divided into three sub-projects: sub-project A will establish the computational framework that simulates the physical-chemical interactions of virus with the water-solid interface; sub-project B will experimentally evaluate the extent and relative importance of physical and chemical processes that lead to virus inactivation; sub-project C will be dedicated to characterizing the microscale distribution of oxidizing chemical species at the solid-water interfaces. The combination of theory and experiment is well suited to overcome the challenges associated with the complex virus-interface system, and to derive a generally valid concept of virus inactivation at solid-water interfaces.
SupportProgram
Origins: /Bund/UBA/UFORDAT
Tags: Blei ? Brunnen ? Sauerstoff ? Schadstoffbelastung ? Betriebswasser ? Feststoff ? Strafrecht ? Bewässerung ? Modellierung ? Blut ? Chemikalien ? Chemisches Verfahren ? Desinfektion ? Rechtsverfahren ? Virus ? Allgemeine Gesundheit ? Grundwasser ? Chemische Reaktion ? Krankheitserreger ? Lebensmittel ? Persistenz ? Produkt ? Ressource ? Umwelt ? Wasserressourcen ? Gewässer ? Wasser ? GEMISCHT ? OBERFLAECHE ? VERTEILUNG ? Virusinaktivierung ? WASSERKOERPER ? WICHTIG ? Art [Spezies] ? EINSATZ ? EXPERIMENT ? BESCHREIBUNG ? PROJEKT ? Buchgrundstück ? SCHNITTSTELLE ? SONSTIG ? Theorie ? KONTAMINIEREN ? MISCHUNG ? UNTERSUCHUNG ? EIN ? VERARBEITEN ?
License: cc-by-nc-nd/4.0
Language: Englisch/English
Time ranges: 2010-01-01 - 2012-12-31
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