Description: Das Projekt "Environmental risk assessment of pharmaceuticals (ERAPHARM)" wird vom Umweltbundesamt gefördert und von ECT Ökotoxikologie GmbH durchgeführt. The overall objective of ERAP harm is to improve and complement existing knowledge and procedures for the environmental risk assessment (ERA) of human and veterinary pharmaceuticals. Based on EU regulatory frameworks on the ERA of pharmaceuticals and on the outcome of previous projects ERAP harm will address the following aspects: It will investigate previously unstudied major routes leading to exposure of the terrestrial and aquatic environment and subsequent fate of pharmaceuticals in surface water and sediment. Factors and processes affecting the behavior of pharmaceuticals in the environment will be studied on the laboratory, semi-field and fieldscale. A scenario-based exposure assessment system will be developed for predicting concentrations of pharmaceuticals in soils, surface waters and sediments and leaching to groundwater. It will be investigated if environmentally relevant concentrations of pharmaceuticals pose a risk to aquatic and terrestrial organisms. Pharmaceuticals and selected transformation products will be screened using in vitro and low complexity bioanalytical tests in order to provide a first hazard characterization and to target higher tier testing. Higher tier test methods will be improved and applied for detecting the effects of long-term, low-level exposure to pharmaceuticals on aquatic and terrestrial invertebrates and fish. It will be evaluated if information on pharmaco- and toxicodynamics in mammalian species can be used to predict effects of pharmaceuticals on environmental organisms. Moreover, the effects of antibiotics on microbial communities will be studied with a main focus on the spread of genetically encoded resistance. Based on the developed approaches recommendations will be provided on how to improve the ERA procedures for pharmaceuticals. A guidance document will be compiled that will be made available to regulators, industry and the scientific community.
Types:
SupportProgram
Origin: /Bund/UBA/UFORDAT
Tags: Antibiotikum ? Fossiler Brennstoff ? Fisch ? Tierarzneimittel ? Main ? Arzneimittel ? Genetik ? Langzeitwirkung ? Meteorologie ? Resistenz ? Schadstoffbelastung ? Skigebiet ? Technologietransfer ? Blei ? Fischtest ? Lagerstätte ? Ökotoxikologie ? Szenario ? Widerspruchsverfahren ? Wirkung ? Industrie ? Oberflächenwasser ? Unterboden ? Innovation ? Energietransport ? Abfallwirtschaft ? Ackerland ? Bodenbelastung ? Bodenorganismen ? Bodenuntersuchung ? Chemikalien ? Energieeinsparung ? Energiespeicher ? Exposition ? in vitro ? Oberflächengewässer ? Politik ? Risikoanalyse ? Sediment ? Grundwasser ? Boden ? Umweltrisikobewertung ? Expositionsanalyse ? Aquatisches Ökosystem ? Gesundheit ? Organismen ? Risiko ? Sicherheit ? Umwelt ? Wasserstand ? Fischerei ? Verkehr ? Forschungseinrichtung ? Gefahr ? Sicherheitsanalyse ? Umweltschutz ? System ? Geowissenschaften ? Soziale Aspekte ? Risiken, Sicherheit ? targeted testing ? Sieb ? Siebung ? Verbleib ? Other Energy Topics ? Renewable Sources of Energy ? angewandt ? ausgewählt ? Empfehlung ? exposure modelling ? fate processes ? specific effects ? Aspekt ? Gemeinschaft ? Resources of the Sea ? Beschreibung ? Dokument ? Scientific Research ? Annäherung ? wissenschaftlich ? FP6-SUSTDEV ? Konzentrat ? transformation products ? verfügbar ? Sicherungsanordnung ? Methode ?
Region: Hessen
Bounding box: 9° .. 9° x 50.55° .. 50.55°
License: cc-by-nc-nd/4.0
Language: Deutsch
Time ranges: 2004-10-01 - 2007-09-30
Webseite zum Förderprojekt
http://www.erapharm.org/ (Webseite)Accessed 1 times.