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IARC Project 'Risk of Thyroid Cancer from Chernobyl'

Description: Das Projekt "IARC Project 'Risk of Thyroid Cancer from Chernobyl'" wird vom Umweltbundesamt gefördert und von Bundesamt für Gesundheit, Abteilung Strahlenschutz durchgeführt. Uncertainties in Individual Doses in a Case-Control Study of Thyroid Cancer after the Chernobyl Accident. A population-based case-control study of thyroid cancer among young people was carried out in the regions of Belarus and Russia that were most heavily contaminated by radioactive fallout from the Chernobyl accident. The study included 2,239 persons, both cases and controls, all aged 0-18 at the time of the accident in 1986. A single uniform method was developed, verified, and applied to all study subjects to reconstruct thyroid doses from intake of 131I via inhalation and ingestion. Although the process of dose reconstruction provides a deterministic (point) estimate of each subject's dose, it is obvious that these dose calculations are also associated with uncertainties. Project goal: The overall objective of the current project is to provide the best possible estimate of thyroid cancer risk following exposure to iodine isotopes and compare it to the risk following external photon radiation, so that all major lessons can be learned from Chernobyl about risk of thyroid cancer following radioiodine exposures . To fulfill this objective, the following operational aims must be achieved : 1) Characterisation and modelling of dosimetric uncertainties for subjects in IARC-led casecontrol study ; 2) Assessment of thyroid cancer risk from iodine isotopes within the IARC coordinated thyroid cancer case-control study taking into account the uncertainties in dosimetry.

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SupportProgram

Origin: /Bund/UBA/UFORDAT

Tags: Inhalation ? Iod ? Ingestion ? Tschernobyl ? Radiojod ? Dosimetrie ? Radioaktiver Niederschlag ? Schadstoffbelastung ? Russland ? Weißrussland ? Schulunterricht ? Strahlenexposition ? Strahlenschutz ? Strahlung ? Fallkontrollstudie ? Mensch ? Dosis ? Exposition ? Studie ? Toxikologische Bewertung ? Modellierung ? Berechnungsverfahren ? Isotop ? Krebserkrankung ? Krebsrisiko ? Population ? Risiko ? Bevölkerung ? Unfall ? Berechnung ? Fallout ? Koordinate ? Unterrichtseinheit ? Deterministische Methode ?

License: cc-by-nc-nd/4.0

Language: Deutsch

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Time ranges: 2006-07-01 - 2008-01-08

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